α-Conotoxin PnIA ( )

Catalog No. M30730 CAS No. 705300-84-1

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Product Name

α-Conotoxin PnIA
Note

Research use only, not for human use.
Brief Description

Selective antagonist of α3β2 nAChR receptors (IC50 values are 9.56 and 252 nM for α3β2 and α7 receptors respectively).
Description

Selective antagonist of α3β2 nAChR receptors (IC50 values are 9.56 and 252 nM for α3β2 and α7 receptors respectively).
Synonyms
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

——
Research Area

——
Indication

——

CAS Number

705300-84-1
Formula Weight

1622.8
Molecular Formula

C65H95N19O22S4
Purity

>98% (HPLC)
Solubility

water:5 mg/mL
SMILES

[H]NCC(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@@H]3CCCN3C(=O)[C@@H]3CCCN3C(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC2=O)C(N)=O)NC1=O
Chemical Name

1. Fainzilber et al (1994) New mollusc-specific α-conotoxins block Aplysia neuronal acetylcholine receptors. Biochemistry 33 9523 PMID:

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